Logo
東海大學奈米科技研究中心-中心成員-中心主任-楊定亞 教授兼理學院院長

楊定亞 教授兼理學院院長

信箱:yang@thu.edu.tw
個人網站:http://web.thu.edu.tw/yang/www/
分機:32228
 

學歷

美國明尼蘇達大學化學博士

經歷

東海大學奈米科技研究中心主任(2017-)
東海大學理學院院長(2015-)
東海大學化學系系主任(2011)
美國新墨西哥州立大學化學系訪問教授(2009)
東海大學化學系系主任(2006-2008)
東海大學教授(2003-)
東海大學副教授(1993-2003)
美國康乃爾大學博士後研究
(1992-1993)

專長

 生物有機化學、有機材料化學

期刊

(60). Chun-Ku Wu and Ding-Yah Yang* "Visible-Light-Mediated Reaction: Synthesis of Quinazolinones from 1,2-Dihydroquinazoline 3-Oxides", RSC Adv. 2016, 6(70), 65988-65994. 
(59). Kiran B. Manjappa, Yu-Ting Peng, Wei-Fang Jhang, and Ding-Yah Yang* "Microwave-promoted, catalyst-free, multi-component reaction of proline, aldehyde, 1,3-diketone: one pot synthesis of pyrrolizidines and pyrrolizinones", Tetrahedron. 2016, 72(6), 853-861.
(58). Kiran B. Manjappa, Jia-Ru Syu, and Ding-Yah Yang* "Visible-Light-Promoted and Yb(OTf)3-Catalyzed Constructions of Coumarin-Pyrrole-(Iso)quinoline-Fused Pentacycles: Synthesis of Lamellarin Core, Lamellarin D Trimethyl Ether, and Lamellarin H", Org. Lett. 2016, 18(2), 332-335.
(57). Shi-Chen Li, Wei-Fang Jhang, Teau-Jiuan Liou, and Ding-Yah Yang* "Photochemical Synthesis of Indazolo[3,2-b]quinazolines and Their Redox-switching Properties", Dyes Pigments. 2015, 114(C), 259-266. 
(56). Kiran B. Manjappa, Wei-Fang Jhang, Shin-Yi Huang, and Ding-Yah Yang* "Microwave-promoted, Metal- and Catalyst-free Decarboxylative a,b-Difunctionlization of Secondary a-Amino Acids via Pseudo Four-component Reactions", Org. Lett. 2014, 16(21), 5690-5693. 
(55). Chun-Ku Wu, Teau-Jiuan Liou, Hao-Yi Wei, Pei-Shan Tsai, and Ding-Yah Yang* "Visible Light Photoredox Catalysis: Aerobic Oxidation of Perimidines to Perimidinones", Tetrahedron 2014, 70(44), 8219-8225. 
(54). Jia-Ru Syu, Chi-Hui Lin, Chiao-Wen Kuo, and Ding-Yah Yang* "Synthesis of Benzofuran-Containing Spirolactones from Diarylcyclopropenones", Tetrahedron Lett. 2014, 55(6), 1207-1211.
(53). Wen-Chung Lin and Ding-Yah Yang* "Photochromism of o-Nitrophenyl-Substituted Oxazabicycles", J. Org. Chem. 2013, 78(23), 11629-12282. 
(52). Yi-Chou Chen and Ding-Yah Yang* "Visible Light-mediated Synthesis of Quinazolines from 1,2-Dihydroquinazoline 3-Oxides", Tetrahedron 2013, 69(48), 10438-10444. 
(51). Wen-Chung Lin and Ding-Yah Yang* "Visible Light Photoredox Catalysis: Synthesis of Indazolo[2,3-a]quinolines from 2-(2-Nitrophenyl)-1,2,3,4- tetrahydroquinolines", Org. Lett. 2013, 15(18), 4862-4865. 
(50). Chi-Hui Lin and Ding-Yah Yang* " Synthesis of Coumarin/Pyrrole-Fused Heterocycles and Their Photochemical and Redox-Switching Properties", Org. Lett. 2013, 15(11), 2802-2805.
(49). Chi-Hui Lin, Rong-Ren Chuang, Pei-Yu Kuo, and Ding-Yah Yang* "Conformation and Photochemical Properties of 3-Benzoyl-4-benzylamino-7-dimethylaminocoumarin", Tetrahedron Lett. 2013, 54(19), 2431-2434. 
(48). Wei-Zhe Chen, Hao-Yi Wei, and Ding-Yah Yang* "Visible Light-sensitive Properties of 1,2-Dimethyl-2-(2-nitrophenyl)-2,3-dihydro-1H-perimidine", Tetrahedron 2013, 69(13), 2775-2781. 
(47). Chia-Lin Wu, Jiu-Haw Yin, Chi-Shin Hwang, Shang-Der Chen, Ding-Yah Yang, and Ding-I Yang* "c-Jun-dependent sulfiredoxin induction mediates BDNF protection against mitochondrial inhibition in rat cortical neurons", Neurobiol. Dis. 2012, 46, 450-462. 
(46). Shih-Hsun Su and Ding-Yah Yang* "Synthesis of a Coumarin/Phenanthridine-Fused Heterocycle as a Lockable Colorimetric Fluorescence Molecular Switch", Arkivoc 2012, vi, 253-263. 
(45). Kuan-Ting Li, Yong-Bo Lin, and Ding-Yah Yang* "One-Pot Synthesis of Pyranocoumarins via Microwave-Assisted Pseudo Multicomponent Reactions and Their Molecular Switching Properties", Org. Lett. 2012, 14(5), 1190-1193.
(44). Jiun-Han Lin, Chi-Hui Lin, and Ding-Yah Yang* "Synthesis of 4-Hydroxy-7-dimethylamino-3-pyrazolinylcoumarins and Their Polarity-Sensitive Properties", Tetrahedron Lett. 2012, 53(7), 778-782. 
(43). Hsiu-Man Lien, Po-Tsun Kuo, Chao-Lu Huang, Jung-Yie Kao, Ho Lin, Ding-Yah Yang and Ya-Yun Lai "Study of the Anti-Proliferative Activity of 5-Substituted 4,7-Dimethoxy-l,3-benzodioxole Derivatives of SY-1 from Antrodia camphorata on Human COLO 205 Colon Cancer Cells", eCAM. 2011, vol. 2011, Article ID. 450529, 8 pages, doi:10.1093/ecam/nep230. 
(42). Hsiu-Man Lien, Hsiao-Wei Lin, Ying-Jan Wang, Li-Ching Chen, Ding-Yah Yang, Ya-Yun Lai, and Yuan-Soon Ho "Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-methyl-l,3-benzodioxole Isolated from the Fruiting Body of Antrodia camphorate", eCAM. 2011, vol. 2011, Article ID 984027, 10 pages, doi:10.1093/ecam/nep020. 
(41). Shadpour Mallakpour,* Fatemeh Rafiemanzelat, Mohammad Ali Zolfigol, Peyman Salehi, and Ding-Yah Yang "Synthesis, characterization, and properties of co-poly(ether-urethane-urea)s containing lariat cryptand 22; Li+ harvesting polymers", Polymer Bulletin. 2011, 67(4), 553-569. 
(40). Jiun-Jia Chen, Kuan-Ting Li, and Ding-Yah Yang* "Synthesis of Coumarin/Phenanthridine-fused Heterocycles and Their Photochemical and Thermochromic Properties" Org. Lett. 2011, 13(7), 1658-1661.
(39). Rong-Ren Chuang, Yi-Ling Chen, and Ding-Yah Yang* "Copper(II) Sensing Properties of Colorimetric and Fluorimetric Chemosensors Based on 7-Dimethylaminocoumarin Chromophores" Sensor Lett. 2010 , 8, 607-612.  
(38). Chi-Hui Lin, Jhih-Rong Chen and Ding-Yah Yang* "Syntheses of Quaternary Carbon-Containing Oxazatricycle and Spiropyran Libraries via Multicomponent Reactions and Their Molecular Switching Properties" J. Comb. Chem. 2010, 12(1), 119-124.  
(37). Jiun-Ting Lai, Yu-Ju Yang, Jian-Hung Lin and Ding-Yah Yang* "Fluorescence Redox Switches Based on the Opening and Closing of an Oxazabicyclic Ring" Synlett 2010, 1, 111-114.  
(36). Chi-Hui Lin, Jing-Fu Jhang and Ding-Yah Yang* "One-Pot Synthesis of Coumarin-Based Oxazabicyclic and Oxazatricyclic Compounds and Their Fluorescence Redox Switching Properties" Org. Lett. 2009, 11(18), 4064-4067. (Impact factor = 5.420) 
(35). Chao-Chen Lin, Cheng-Chih Hsieh, Ya-Chien Yu, Chin-Hung Lai, Chin-Neng Huang, Pei-Yu Kuo, Chi-Hui Lin, Ding-Yah Yang,* and Pi-Tai Chou* "Dual Flourescent Photochromic Colorants Bearing Pyrano[3,2-c]chromen-5-one Moiety" J. Phys. Chem. 2009, 113(33), 9321-9328. (Impact factor = 2.899)
(34). Jiun-Ting Lai, Chun-Han Lin, Yu-Ju Yang and Ding-Yah Yang* "One-pot Tandem Synthesis of a Coumarin/Naphthoquinone Monoimine-based Oxazabicycle and Its Fluorescence Redox-switching Properties" Chem. Lett. 2009, 38(6), 590-591. (Impact factor = 1.460) 
(33). Pei-Yu Kuo, Rong-Ren Chuang and Ding-Yah Yang* "Reactions of 3-Benzoyl-7-dimethylamino-4-hydroxycoumarin and Their Potential Applications" Mol. Divers. 2009, 13(2), 253-260. (Impact factor = 2.071) 
(32). Jhih-Rong Chen and Ding-Yah Yang* "Design and Synthesis of an o-Hydroxyphenyl-Containing Spiropyran Thermochromic Colorant" Org. Lett. 2009, 11(8), 1769-1772. (Impact factor = 5.420) 
(31). Jhih-Rong Chen, Jen-Bing Wong, Pei-Yu Kuo and Ding-Yah Yang* "Synthesis and characterization of coumarin-based spiropyran photochromic colorants" Org. Lett. 2008, 10(21), 4823-4826. 
(30). Pei-Yu Kuo and Ding-Yah Yang* "3-Acetyl-4-methoxy-7-N,N-dimethylaminocoumarin: a fluorescent protecting group for primary amines" J. Org. Chem. 2008, 73(16), 6455-6458.
(29). Chin-Neng Huang, Rong-Ren Chuang, Pei-Yu Kuo and Ding-Yah Yang* "Synthesis, characterization and redox property of 3-(2-phenyl-4H-thiochromen-4-yildene)-3H-chromene-2,4-diones" Synlett 2008, (12), 1825-1828. 
(28). Jiun-Ting Lai, Pei-Shan Shieh, Wei-Hao Huang and Ding-Yah Yang* "Syntheses of oxazabicycle library via one-pot tandem reactions" J. Comb. Chem. 2008, 10(3), 381-386. 
(27). Ding-Yah Yang,* You-Sheng Chen, Pei-Yu Kuo, Jiun-Ting Lai, Chang-Ming Jiang, Chin-Hung Lai, Yong-Hong Liao, and Pi-Tai Chou* "Novel oxazabicycles as a new class of photochromic colorants" Org. Lett. 2007, 9(25), 5287-5290. 
(26). Tien-Lan Shie, Chi-Hui Lin, Shih-Lun Lin and Ding-Yah Yang* "Synthesis of 1,1,3-trisubstituted naphtho[2,3-c]pyran-5,10-dione derivatives as potential redox switches" Eur. J. Org. Chem. 2007, (29), 4831-4836. 
(25). Jiun-Ting Lai, Pei-Yu Kuo, Yung-Her Gau and Ding-Yah Yang* "Synthesis and characterization of coumarin and dimedone-derived diazabicycles" Tetrahedron Lett. 2007, 48(44), 7796-7800.
(24). Chin-Neng Huang , Pei-Yu Kuo, Chi-Hui Lin and Ding-Yah Yang* "Synthesis and characterization of 2H -pyrano[3,2- c]coumarin derivatives and their photochromic and redox properties" Tetrahedron 2007, 63(40), 10025-10033. 
(23). Shih-Lun Lin, Pei-Yu Kuo and Ding-Yah Yang* "Design and synthesis of a coumarin-based acidichromic colorant" Molecules 2007, 12(7),1316-1324. 
(22). Jen-Fei Wang, Yuan-Xiu Liao, Pei-Yu Kuo, Yung-Her Gau and Ding-Yah Yang* "Synthesis and characterization of [1]benzopyrano[4,3-d][1,3]-benzooxazocin-13-one and its derivatives" Synlett 2006, (17), 2791-2794. 
(21). Pei-Yu Kuo, Tien-Lan Shie, You-Sheng Chen, Jiun-Ting Lai and Ding-Yah Yang* "Enzyme inhibition potency enhancement by active site metal chelating and hydrogen bonding induced conformation-restricted cyclopropanecarbonyl derivatives" Bioorg. Med. Chem. Lett. 2006, 16(23), 6024-6027. 
(20). You-Sheng Chen, Pei-Yu Kuo, Tien-Lan Shie and Ding-Yah Yang* "Structure, reactivity and application of some triketone derivatives" Tetrahedron 2006, 62(40), 9410-9416.
(19). Ding-Yah Yang, Gustavo H. Goldman, et al. "Transcriptome analysis of Paracoccidioides brasiliensis cells undergoing mycelium-to-yeast transition" Eukaryotic Cell 2005, 4(12), 2115-2128. 
(18). Ching-Tsan Lin, Jen-Hao Shih, Chung-Ling Chen and Ding-Yah Yang* "Synthesis of novel triketone-based acidichromic colorants" Tetrahedron Lett. 2005, 46(30), 5033-5037. 
(17). Ding-Uei Chen, Pei-Yu Kuo and Ding-Yah Yang* "Design and synthesis of novel diphenacoum-derived, conformation-restricted vitamin K 2,3-epoxide reductase inhibitors" Bioorg. Med. Chem. Lett. 2005, 15(10), 2665-2668. 
(16). Ding-Yah Yang* "4-Hydroxyphenylpyruvate dioxygenase as a drug discovery target" Drug News Perspect. 2003, 16(8), 493-496. 
(15). Hun-Ge Liu, Chung-Shieh Wu, Jen-Fei Wang, and Ding-Yah Yang* "Isomerization of enol esters derived from 2-acyl-1,3-cyclohexanediones: mechanism and driving force" Tetrahedron Lett. 2003, 44(15), 3137-3141.
(14). Jian-Lin Huang, Hun-Ge Liu, and Ding-Yah Yang* "Acylcyclohexanedione derivatives as potential in vivo sequential inhibitors of 4-hydroxyphenylpyruvate dioxygenase and GA20 3-hydroxylase" Bioorg. Med. Chem. Lett. 2003, 13(5), 927-930. 
(13). Yuan-Xiu Liao, Pei-Yu Kuo, and Ding-Yah Yang* "Efficient synthesis of trisubstituted [1] benzopyrano[4,3-b]pyrrol-4(1H)-one derivatives from 4-hydroxycoumarin" Tetrahedron Lett. 2003, 44(8), 1599-1602. 
(12). Mei-Lan Huang, Ding-Yah Yang, Zhi-Cai Shang, Jian-Wei Zou and Qing-SenYu "Studies on the tautomerism of benzoylcyclohexane-1,3-dione and its derivatives by ab initio calculation" Chinese J. Struc. Chem. 2002, 21(6), 678-682. 
(11). Meilan Huang, Ding-Yah Yang, Zhicai Shang, Jianwei Zou and Qingsen Yu "CoMFA of two classes o f4-hydroxyphenylpyruvate dioxygenase inhibitors" Acta. Chim. Sinica. 2002, 60(9), 1558-1563. 
(10). Mei-Lan Huang, Ding-Yah Yang, Zhi-Cai Shang, and Qing-Sen Yu "Theoretical studies on tautomerism of benzoylcyclohexane-1,3-dione and its derivatives" Journal of Molecular Structure (Theochem) 2002, 589, 321-328.
(9). Mei-Lan Huang, Ding-Yah Yang, ZhiCcai Shang, Jian-Wei Zou and Qing-Sen Yu "3-D QSAR studies on 4-hydroxyphenylpyruvate dioxygenase inhibitors by comparative molecular field analysis (CoMFA)" Bioorg. Med. Chem. Lett. 2002, 12(17), 2271-2275. 
(8). Yun-Loung Lin, Jian-Lin Huang, Chung-Shieh Wu, Hung-Ge Liu, and Ding-Yah Yang* "Design, synthesis, and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hydroxyphenyl-pyruvate dioxygenase" Bioorg. Med. Chem. Lett. 2002, 12(13), 1709-1713. 
(7). Chung-Shieh Wu, Jian-Lin Huang, Yang-Sheng Sun, and Ding-Yah Yang* "Mode of action of 4-hydroxyphenylpyruvate dioxygenase inhibition by triketone-type inhibitors" J. Med. Chem. 2002, 45(11), 2222-2228. 
(6). Yung-Lung Lin, Chung-Shieh Wu, Shean-Woei Lin, Jian-Lin Huang, Yang-Sheng Sun, and Ding-Yah Yang* "SAR studies of 3-cyclo-propane-carbonyloxy-2-cyclohexen-1-one as inhibitors of 4-hydroxyphenylpyruvate dioxygenase" Bioorg. Med. Chem. 2002, 10(3), 685-690. 
(5). Shean-Woei Lin, Yun-Loung Lin, Tzu-Ching Lin, and Ding-Yah Yang* "Discovery of a potent, non-triketone type inhibitor of 4-hydroxyphenyl-pyruvate dioxygenase" Bioorg. Med. Chem. Lett. 2000, 10(11), 1297-1298.
(4). Yung-Lung Lin, Chung-Shieh Wu, Shean-Woei Lin, and Ding-Yah Yang* "SAR studies of 2-o-substituted-benzoyl- and 2-alkanoyl-cyclo-hexane-1,3-diones as inhibitors of 4-hydroxyphenylpyruvate dioxygenase" Bioorg. Med. Chem. Lett. 2000, 10(9), 843-845. 
(3). Tung-Shen Ling, Shi Shiu, and Ding-Yah Yang* "Design and synthesis of 3-fluoro-2-oxo-3-phenylpropionic acid derivatives as potent inhibitors of 4-hydroxyphenylpyruvate dioxygenase from pig liver" Bioorg. Med. Chem. 1999, 7(7), 1459-1465. 
(2). Shean-Woei Lin and Ding-Yah Yang* "Inhibition of 4-hydroxyphenyl pyruvate dioxygenase by sethoxydim, a potent inhibitor of acetyl-coenzyme a carboxylase" Bioorg. Med. Chem. Lett. 1999, 9(4), 551-554. 
(1). Bor-Cherng Chen, Shi Shiu and Ding-Yah Yang* "A general procedure for synthesis of NG-alkyl, and NG-aryl-L-arginines as potential nitric oxide synthase inhibitors" J. Chin. Chem. Soc. 1998, 45(4), 549-553.

 

學歷

美國明尼蘇達大學化學博士

經歷

東海大學奈米科技研究中心主任(2017-)
東海大學理學院院長(2015-)
東海大學化學系系主任(2011)
美國新墨西哥州立大學化學系訪問教授(2009)
東海大學化學系系主任(2006-2008)
東海大學教授(2003-)
東海大學副教授(1993-2003)
美國康乃爾大學博士後研究
(1992-1993)

專長

 生物有機化學、有機材料化學

期刊

(60). Chun-Ku Wu and Ding-Yah Yang* "Visible-Light-Mediated Reaction: Synthesis of Quinazolinones from 1,2-Dihydroquinazoline 3-Oxides", RSC Adv. 2016, 6(70), 65988-65994. 
(59). Kiran B. Manjappa, Yu-Ting Peng, Wei-Fang Jhang, and Ding-Yah Yang* "Microwave-promoted, catalyst-free, multi-component reaction of proline, aldehyde, 1,3-diketone: one pot synthesis of pyrrolizidines and pyrrolizinones", Tetrahedron. 2016, 72(6), 853-861.
(58). Kiran B. Manjappa, Jia-Ru Syu, and Ding-Yah Yang* "Visible-Light-Promoted and Yb(OTf)3-Catalyzed Constructions of Coumarin-Pyrrole-(Iso)quinoline-Fused Pentacycles: Synthesis of Lamellarin Core, Lamellarin D Trimethyl Ether, and Lamellarin H", Org. Lett. 2016, 18(2), 332-335.
(57). Shi-Chen Li, Wei-Fang Jhang, Teau-Jiuan Liou, and Ding-Yah Yang* "Photochemical Synthesis of Indazolo[3,2-b]quinazolines and Their Redox-switching Properties", Dyes Pigments. 2015, 114(C), 259-266. 
(56). Kiran B. Manjappa, Wei-Fang Jhang, Shin-Yi Huang, and Ding-Yah Yang* "Microwave-promoted, Metal- and Catalyst-free Decarboxylative a,b-Difunctionlization of Secondary a-Amino Acids via Pseudo Four-component Reactions", Org. Lett. 2014, 16(21), 5690-5693. 
(55). Chun-Ku Wu, Teau-Jiuan Liou, Hao-Yi Wei, Pei-Shan Tsai, and Ding-Yah Yang* "Visible Light Photoredox Catalysis: Aerobic Oxidation of Perimidines to Perimidinones", Tetrahedron 2014, 70(44), 8219-8225. 
(54). Jia-Ru Syu, Chi-Hui Lin, Chiao-Wen Kuo, and Ding-Yah Yang* "Synthesis of Benzofuran-Containing Spirolactones from Diarylcyclopropenones", Tetrahedron Lett. 2014, 55(6), 1207-1211.
(53). Wen-Chung Lin and Ding-Yah Yang* "Photochromism of o-Nitrophenyl-Substituted Oxazabicycles", J. Org. Chem. 2013, 78(23), 11629-12282. 
(52). Yi-Chou Chen and Ding-Yah Yang* "Visible Light-mediated Synthesis of Quinazolines from 1,2-Dihydroquinazoline 3-Oxides", Tetrahedron 2013, 69(48), 10438-10444. 
(51). Wen-Chung Lin and Ding-Yah Yang* "Visible Light Photoredox Catalysis: Synthesis of Indazolo[2,3-a]quinolines from 2-(2-Nitrophenyl)-1,2,3,4- tetrahydroquinolines", Org. Lett. 2013, 15(18), 4862-4865. 
(50). Chi-Hui Lin and Ding-Yah Yang* " Synthesis of Coumarin/Pyrrole-Fused Heterocycles and Their Photochemical and Redox-Switching Properties", Org. Lett. 2013, 15(11), 2802-2805.
(49). Chi-Hui Lin, Rong-Ren Chuang, Pei-Yu Kuo, and Ding-Yah Yang* "Conformation and Photochemical Properties of 3-Benzoyl-4-benzylamino-7-dimethylaminocoumarin", Tetrahedron Lett. 2013, 54(19), 2431-2434. 
(48). Wei-Zhe Chen, Hao-Yi Wei, and Ding-Yah Yang* "Visible Light-sensitive Properties of 1,2-Dimethyl-2-(2-nitrophenyl)-2,3-dihydro-1H-perimidine", Tetrahedron 2013, 69(13), 2775-2781. 
(47). Chia-Lin Wu, Jiu-Haw Yin, Chi-Shin Hwang, Shang-Der Chen, Ding-Yah Yang, and Ding-I Yang* "c-Jun-dependent sulfiredoxin induction mediates BDNF protection against mitochondrial inhibition in rat cortical neurons", Neurobiol. Dis. 2012, 46, 450-462. 
(46). Shih-Hsun Su and Ding-Yah Yang* "Synthesis of a Coumarin/Phenanthridine-Fused Heterocycle as a Lockable Colorimetric Fluorescence Molecular Switch", Arkivoc 2012, vi, 253-263. 
(45). Kuan-Ting Li, Yong-Bo Lin, and Ding-Yah Yang* "One-Pot Synthesis of Pyranocoumarins via Microwave-Assisted Pseudo Multicomponent Reactions and Their Molecular Switching Properties", Org. Lett. 2012, 14(5), 1190-1193.
(44). Jiun-Han Lin, Chi-Hui Lin, and Ding-Yah Yang* "Synthesis of 4-Hydroxy-7-dimethylamino-3-pyrazolinylcoumarins and Their Polarity-Sensitive Properties", Tetrahedron Lett. 2012, 53(7), 778-782. 
(43). Hsiu-Man Lien, Po-Tsun Kuo, Chao-Lu Huang, Jung-Yie Kao, Ho Lin, Ding-Yah Yang and Ya-Yun Lai "Study of the Anti-Proliferative Activity of 5-Substituted 4,7-Dimethoxy-l,3-benzodioxole Derivatives of SY-1 from Antrodia camphorata on Human COLO 205 Colon Cancer Cells", eCAM. 2011, vol. 2011, Article ID. 450529, 8 pages, doi:10.1093/ecam/nep230. 
(42). Hsiu-Man Lien, Hsiao-Wei Lin, Ying-Jan Wang, Li-Ching Chen, Ding-Yah Yang, Ya-Yun Lai, and Yuan-Soon Ho "Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-methyl-l,3-benzodioxole Isolated from the Fruiting Body of Antrodia camphorate", eCAM. 2011, vol. 2011, Article ID 984027, 10 pages, doi:10.1093/ecam/nep020. 
(41). Shadpour Mallakpour,* Fatemeh Rafiemanzelat, Mohammad Ali Zolfigol, Peyman Salehi, and Ding-Yah Yang "Synthesis, characterization, and properties of co-poly(ether-urethane-urea)s containing lariat cryptand 22; Li+ harvesting polymers", Polymer Bulletin. 2011, 67(4), 553-569. 
(40). Jiun-Jia Chen, Kuan-Ting Li, and Ding-Yah Yang* "Synthesis of Coumarin/Phenanthridine-fused Heterocycles and Their Photochemical and Thermochromic Properties" Org. Lett. 2011, 13(7), 1658-1661.
(39). Rong-Ren Chuang, Yi-Ling Chen, and Ding-Yah Yang* "Copper(II) Sensing Properties of Colorimetric and Fluorimetric Chemosensors Based on 7-Dimethylaminocoumarin Chromophores" Sensor Lett. 2010 , 8, 607-612.  
(38). Chi-Hui Lin, Jhih-Rong Chen and Ding-Yah Yang* "Syntheses of Quaternary Carbon-Containing Oxazatricycle and Spiropyran Libraries via Multicomponent Reactions and Their Molecular Switching Properties" J. Comb. Chem. 2010, 12(1), 119-124.  
(37). Jiun-Ting Lai, Yu-Ju Yang, Jian-Hung Lin and Ding-Yah Yang* "Fluorescence Redox Switches Based on the Opening and Closing of an Oxazabicyclic Ring" Synlett 2010, 1, 111-114.  
(36). Chi-Hui Lin, Jing-Fu Jhang and Ding-Yah Yang* "One-Pot Synthesis of Coumarin-Based Oxazabicyclic and Oxazatricyclic Compounds and Their Fluorescence Redox Switching Properties" Org. Lett. 2009, 11(18), 4064-4067. (Impact factor = 5.420) 
(35). Chao-Chen Lin, Cheng-Chih Hsieh, Ya-Chien Yu, Chin-Hung Lai, Chin-Neng Huang, Pei-Yu Kuo, Chi-Hui Lin, Ding-Yah Yang,* and Pi-Tai Chou* "Dual Flourescent Photochromic Colorants Bearing Pyrano[3,2-c]chromen-5-one Moiety" J. Phys. Chem. 2009, 113(33), 9321-9328. (Impact factor = 2.899)
(34). Jiun-Ting Lai, Chun-Han Lin, Yu-Ju Yang and Ding-Yah Yang* "One-pot Tandem Synthesis of a Coumarin/Naphthoquinone Monoimine-based Oxazabicycle and Its Fluorescence Redox-switching Properties" Chem. Lett. 2009, 38(6), 590-591. (Impact factor = 1.460) 
(33). Pei-Yu Kuo, Rong-Ren Chuang and Ding-Yah Yang* "Reactions of 3-Benzoyl-7-dimethylamino-4-hydroxycoumarin and Their Potential Applications" Mol. Divers. 2009, 13(2), 253-260. (Impact factor = 2.071) 
(32). Jhih-Rong Chen and Ding-Yah Yang* "Design and Synthesis of an o-Hydroxyphenyl-Containing Spiropyran Thermochromic Colorant" Org. Lett. 2009, 11(8), 1769-1772. (Impact factor = 5.420) 
(31). Jhih-Rong Chen, Jen-Bing Wong, Pei-Yu Kuo and Ding-Yah Yang* "Synthesis and characterization of coumarin-based spiropyran photochromic colorants" Org. Lett. 2008, 10(21), 4823-4826. 
(30). Pei-Yu Kuo and Ding-Yah Yang* "3-Acetyl-4-methoxy-7-N,N-dimethylaminocoumarin: a fluorescent protecting group for primary amines" J. Org. Chem. 2008, 73(16), 6455-6458.
(29). Chin-Neng Huang, Rong-Ren Chuang, Pei-Yu Kuo and Ding-Yah Yang* "Synthesis, characterization and redox property of 3-(2-phenyl-4H-thiochromen-4-yildene)-3H-chromene-2,4-diones" Synlett 2008, (12), 1825-1828. 
(28). Jiun-Ting Lai, Pei-Shan Shieh, Wei-Hao Huang and Ding-Yah Yang* "Syntheses of oxazabicycle library via one-pot tandem reactions" J. Comb. Chem. 2008, 10(3), 381-386. 
(27). Ding-Yah Yang,* You-Sheng Chen, Pei-Yu Kuo, Jiun-Ting Lai, Chang-Ming Jiang, Chin-Hung Lai, Yong-Hong Liao, and Pi-Tai Chou* "Novel oxazabicycles as a new class of photochromic colorants" Org. Lett. 2007, 9(25), 5287-5290. 
(26). Tien-Lan Shie, Chi-Hui Lin, Shih-Lun Lin and Ding-Yah Yang* "Synthesis of 1,1,3-trisubstituted naphtho[2,3-c]pyran-5,10-dione derivatives as potential redox switches" Eur. J. Org. Chem. 2007, (29), 4831-4836. 
(25). Jiun-Ting Lai, Pei-Yu Kuo, Yung-Her Gau and Ding-Yah Yang* "Synthesis and characterization of coumarin and dimedone-derived diazabicycles" Tetrahedron Lett. 2007, 48(44), 7796-7800.
(24). Chin-Neng Huang , Pei-Yu Kuo, Chi-Hui Lin and Ding-Yah Yang* "Synthesis and characterization of 2H -pyrano[3,2- c]coumarin derivatives and their photochromic and redox properties" Tetrahedron 2007, 63(40), 10025-10033. 
(23). Shih-Lun Lin, Pei-Yu Kuo and Ding-Yah Yang* "Design and synthesis of a coumarin-based acidichromic colorant" Molecules 2007, 12(7),1316-1324. 
(22). Jen-Fei Wang, Yuan-Xiu Liao, Pei-Yu Kuo, Yung-Her Gau and Ding-Yah Yang* "Synthesis and characterization of [1]benzopyrano[4,3-d][1,3]-benzooxazocin-13-one and its derivatives" Synlett 2006, (17), 2791-2794. 
(21). Pei-Yu Kuo, Tien-Lan Shie, You-Sheng Chen, Jiun-Ting Lai and Ding-Yah Yang* "Enzyme inhibition potency enhancement by active site metal chelating and hydrogen bonding induced conformation-restricted cyclopropanecarbonyl derivatives" Bioorg. Med. Chem. Lett. 2006, 16(23), 6024-6027. 
(20). You-Sheng Chen, Pei-Yu Kuo, Tien-Lan Shie and Ding-Yah Yang* "Structure, reactivity and application of some triketone derivatives" Tetrahedron 2006, 62(40), 9410-9416.
(19). Ding-Yah Yang, Gustavo H. Goldman, et al. "Transcriptome analysis of Paracoccidioides brasiliensis cells undergoing mycelium-to-yeast transition" Eukaryotic Cell 2005, 4(12), 2115-2128. 
(18). Ching-Tsan Lin, Jen-Hao Shih, Chung-Ling Chen and Ding-Yah Yang* "Synthesis of novel triketone-based acidichromic colorants" Tetrahedron Lett. 2005, 46(30), 5033-5037. 
(17). Ding-Uei Chen, Pei-Yu Kuo and Ding-Yah Yang* "Design and synthesis of novel diphenacoum-derived, conformation-restricted vitamin K 2,3-epoxide reductase inhibitors" Bioorg. Med. Chem. Lett. 2005, 15(10), 2665-2668. 
(16). Ding-Yah Yang* "4-Hydroxyphenylpyruvate dioxygenase as a drug discovery target" Drug News Perspect. 2003, 16(8), 493-496. 
(15). Hun-Ge Liu, Chung-Shieh Wu, Jen-Fei Wang, and Ding-Yah Yang* "Isomerization of enol esters derived from 2-acyl-1,3-cyclohexanediones: mechanism and driving force" Tetrahedron Lett. 2003, 44(15), 3137-3141.
(14). Jian-Lin Huang, Hun-Ge Liu, and Ding-Yah Yang* "Acylcyclohexanedione derivatives as potential in vivo sequential inhibitors of 4-hydroxyphenylpyruvate dioxygenase and GA20 3-hydroxylase" Bioorg. Med. Chem. Lett. 2003, 13(5), 927-930. 
(13). Yuan-Xiu Liao, Pei-Yu Kuo, and Ding-Yah Yang* "Efficient synthesis of trisubstituted [1] benzopyrano[4,3-b]pyrrol-4(1H)-one derivatives from 4-hydroxycoumarin" Tetrahedron Lett. 2003, 44(8), 1599-1602. 
(12). Mei-Lan Huang, Ding-Yah Yang, Zhi-Cai Shang, Jian-Wei Zou and Qing-SenYu "Studies on the tautomerism of benzoylcyclohexane-1,3-dione and its derivatives by ab initio calculation" Chinese J. Struc. Chem. 2002, 21(6), 678-682. 
(11). Meilan Huang, Ding-Yah Yang, Zhicai Shang, Jianwei Zou and Qingsen Yu "CoMFA of two classes o f4-hydroxyphenylpyruvate dioxygenase inhibitors" Acta. Chim. Sinica. 2002, 60(9), 1558-1563. 
(10). Mei-Lan Huang, Ding-Yah Yang, Zhi-Cai Shang, and Qing-Sen Yu "Theoretical studies on tautomerism of benzoylcyclohexane-1,3-dione and its derivatives" Journal of Molecular Structure (Theochem) 2002, 589, 321-328.
(9). Mei-Lan Huang, Ding-Yah Yang, ZhiCcai Shang, Jian-Wei Zou and Qing-Sen Yu "3-D QSAR studies on 4-hydroxyphenylpyruvate dioxygenase inhibitors by comparative molecular field analysis (CoMFA)" Bioorg. Med. Chem. Lett. 2002, 12(17), 2271-2275. 
(8). Yun-Loung Lin, Jian-Lin Huang, Chung-Shieh Wu, Hung-Ge Liu, and Ding-Yah Yang* "Design, synthesis, and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hydroxyphenyl-pyruvate dioxygenase" Bioorg. Med. Chem. Lett. 2002, 12(13), 1709-1713. 
(7). Chung-Shieh Wu, Jian-Lin Huang, Yang-Sheng Sun, and Ding-Yah Yang* "Mode of action of 4-hydroxyphenylpyruvate dioxygenase inhibition by triketone-type inhibitors" J. Med. Chem. 2002, 45(11), 2222-2228. 
(6). Yung-Lung Lin, Chung-Shieh Wu, Shean-Woei Lin, Jian-Lin Huang, Yang-Sheng Sun, and Ding-Yah Yang* "SAR studies of 3-cyclo-propane-carbonyloxy-2-cyclohexen-1-one as inhibitors of 4-hydroxyphenylpyruvate dioxygenase" Bioorg. Med. Chem. 2002, 10(3), 685-690. 
(5). Shean-Woei Lin, Yun-Loung Lin, Tzu-Ching Lin, and Ding-Yah Yang* "Discovery of a potent, non-triketone type inhibitor of 4-hydroxyphenyl-pyruvate dioxygenase" Bioorg. Med. Chem. Lett. 2000, 10(11), 1297-1298.
(4). Yung-Lung Lin, Chung-Shieh Wu, Shean-Woei Lin, and Ding-Yah Yang* "SAR studies of 2-o-substituted-benzoyl- and 2-alkanoyl-cyclo-hexane-1,3-diones as inhibitors of 4-hydroxyphenylpyruvate dioxygenase" Bioorg. Med. Chem. Lett. 2000, 10(9), 843-845. 
(3). Tung-Shen Ling, Shi Shiu, and Ding-Yah Yang* "Design and synthesis of 3-fluoro-2-oxo-3-phenylpropionic acid derivatives as potent inhibitors of 4-hydroxyphenylpyruvate dioxygenase from pig liver" Bioorg. Med. Chem. 1999, 7(7), 1459-1465. 
(2). Shean-Woei Lin and Ding-Yah Yang* "Inhibition of 4-hydroxyphenyl pyruvate dioxygenase by sethoxydim, a potent inhibitor of acetyl-coenzyme a carboxylase" Bioorg. Med. Chem. Lett. 1999, 9(4), 551-554. 
(1). Bor-Cherng Chen, Shi Shiu and Ding-Yah Yang* "A general procedure for synthesis of NG-alkyl, and NG-aryl-L-arginines as potential nitric oxide synthase inhibitors" J. Chin. Chem. Soc. 1998, 45(4), 549-553.